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New drug candidates against COVID19 predicted by Cortex were successfully tested in the lab.

Our deep learning-based approach to Quantitative-Structure-Activity Relationship (QSAR) can predict thousands of pharmacological properties in all therapeutic areas, and for any compound.

Among these targets, we looked at a number of predictions relating to COVID19, including:

Based on these predictions, we selected compounds with high antiviral potential against SARS-CoV-2 among drugs in human trials for other indications. These compounds were never investigated for their potential antiviral activity in general, and against SARS-CoV-2 in particular.

The compounds were tested in vitro by an independent laboratory at Aarhus University (Denmark). The results showed that our candidates had strong antiviral activity in SARS-CoV2 infected cells and none of them was toxic at the active doses.

These results demonstrate our predictions’ outstanding accuracy and provide a glimpse of their immense potential for drug discovery.

If you are a potential customer, collaborator or investor, feel free to contact us to learn more about this experiment.